Ribosomes
Ribosome's Size
Ribosomes comprise of two subunits that are composed and function as one to translate the mRNA into a polypeptide chain and protein synthesis.They vary in size between prokaryotic cells and eukaryotic cells.
The prokaryotic ribosome is comprised of a 30s (Svedberg) subunit and a 50s (Svedberg) subunit meaning 70s for the entire organelle equal to the molecular weight of 2.7×106 Daltons. And Eukaryotic cell comprise of a 40s (Svedberg) subunit and a 60s (Svedberg) subunit which means 80s (Svedberg) for the entire organelle which is equal to the molecular weight of 4×106 Daltons.
- The ribosome word is derived – ‘ribo’ from ribonucleic acid and ‘somes’ from the Greek word ‘soma’ which means ‘body’.
- Ribosomes are tiny spheroidal dense particles (of 150 to 200 A0 diameters) that are primarily found in most prokaryotic and eukaryotic.
- They are sites of protein synthesis.
- They are structures containing approximately equal amounts of RNA and proteins and serve as a molecules involved in protein synthesis.
- The ribosomes occur in cells, both prokaryotic and eukaryotic cells.
- In prokaryotic cells, the ribosomes often occur freely in the cytoplasm.
- In eukaryotic cells, the ribosomes either occur freely in the cytoplasm or remain attached to the outer surface of the membrane of the endoplasmic reticulum.
- The location of the ribosomes in a cell determines what kind of protein it makes.
- If the ribosomes are floating freely throughout the cell, it will make proteins that will be utilized within the cell itself.
- When ribosomes are attached to the endoplasmic reticulum, it is referred to as rough endoplasmic reticulum or rough ER.
- Proteins made on the rough ER are used for usage inside the cell or outside the cell.
- The number of ribosomes in a cell depends on the activity of the cell.
- On average in a mammalian cell, there can be about 10 million ribosomes.
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